The Olofsson Research Group

 

Publications

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2024
Hypervalent iodine chemistry with a mechanochemical twist
Sayad Doobary,* Miguel M. de Vries Ibáñez and Berit Olofsson*
Green Chem. 2024, 26, 11518-11523. Link (open access) PDF
Selected as 2024 HOT Green Chemistry article!

Nanocellulose: New Horizons in Organic Chemistry and Beyond (Perspective)
Sayad Doobary, Varvara Apostolopoulou Kalkavoura, Aji P. Mathew* and Berit Olofsson*
Chem 2024, 10, 3279-3293. Link (open access) PDF


Transition Metal-Free C-Diarylations to reach All-Carbon Quaternary Centers
Shobhan Mondal, Benjamin Gunschera and Berit Olofsson*
JACS Au 2024, 4, 2832-2837. Link (open access) PDF

Cyclopropenium functionalisation
Sayad Doobary* and Berit Olofsson*
Nature Chemistry 2024, 16, 847-848. Link (open access link)
A News & Views text on Waser's cool paper about cyclopropenium benziodoxoles.
Structure-reactivity analysis of novel hypervalent iodine reagents in S-vinylation of thiols
Sayad Doobary, Ester Maria Di Tommaso, Alexandru Postole, A. Ken Inge and Berit Olofsson*
Front. Chem. 2024, 12:1376948. Link (open access) PDF
Invited paper to special issue of Women in Chemistry 2023

2023
Synthesis of Complex Diarylamines through a Ring-Opening Difunctionalization Strategy
Erika Linde and Berit Olofsson*
Angew. Chem. Int. Ed. 2023, e202310921. Link (open access) PDF
Angew. Chem. 2023, e202310921.
Preliminary version in ChemRxiv 2023. Link (open access)

Regioselective Arylations via Aryne Intermediates (Mechanism of the month)
Shobhan Mondal, and Berit Olofsson*
Trends in Chemistry 2023, 5, 404-405. Link (open access) PDF

Advancements in the synthesis of diaryliodonium salts: updated protocols
Erika Linde, Shobhan Mondal and Berit Olofsson*
Adv. Synth. Catal. 2023, 365, 2751-2756. Link (open access) PDF
VIP paper in the invited issue on Iodine in Catalysis and Organic Synthesis
Preliminary version in ChemRxiv 2023. Link (open access)

Ortho-Functionalization of Azobenzenes via Hypervalent Iodine Reagents
Ester Maria Di Tommaso, Melanie Walther, Anne Staubitz,* and Berit Olofsson*
Chem. Commun. 2023, 59, 5047-5050. Link (open access) PDF
Selected as HOT articles 2023!
Preliminary version in ChemRxiv 2023. Link (open access)

Stereoselective Photoredox-Catalyzed Vinylations to Functionalized Alkenes and C-Glycosides
Kumar Bhaskar Pal, Ester Maria Di Tommaso, A. Ken Inge, and Berit Olofsson*
Angew. Chem. Int. Ed. 2023, e202301368. Link (open access) PDF
Also featured in Hot Topic: Photocatalysis in ChemPhotoChem!
Preliminary version in ChemRxiv 2023. Link (open access)

Transition Metal-Free Difunctionalization of Sulfur Nucleophiles
Shobhan Mondal, Ester Maria Di Tommaso and Berit Olofsson*
Angew. Chem. Int. Ed. 2023, 62, e202216296. Link (open access) PDF
Preliminary version in ChemRxiv 2022. Link (open access)

2022
A One-Pot Cascade Protocol for Diarylation of Amines and Water
Erika Linde and Berit Olofsson*
STAR Protocols, 2022, 3, 101700. Link (open access) PDF
Invited paper based on the methodology presented in our Chem paper.

Synthesis of Cyclic and Acyclic ortho-Aryloxy Diaryliodonium Salts for Chemoselective Functionalizations
Erika Linde, Niels Knippenberg and Berit Olofsson*
Chem. Eur. J. 2022, 28, e202202453. Link (open access) PDF
Invited paper to Special Edition for 8th EuChemS Chemistry Congress (ECC8).

Explaining Regio-Divergent Vinylations with Vinylbenziodoxolones
Ester Maria Di Tommaso, Per-Ola Norrby and Berit Olofsson*
Angew. Chem. Int. Ed. 2022, 61, e202206347. Link (open access) PDF
Preliminary version in ChemRxiv 2022Link (open access)

Diarylation of N- and O-nucleophiles through a metal-free cascade reaction
Erika Linde, David Bulfield, Gabriella Kervefors, Nibadita Purkait and Berit Olofsson*
Chem 2022, 8, 850-865. Link (open access) PDF
Preliminary version in ChemRxiv 2021. Link (open acess)
Read Erika's profile and Mike Greaney's preview of the paper in Chem!

2021
Metal-Free N-Arylation of Amino Acid Esters
Gabriella Kervefors, Leonard Kersting and Berit Olofsson*
Hot paper in Chem. Eur. J. 2021, 27, 5790-5795. Link (open access) PDF

Biological Studies of O-Aryl Galactosides as Galectin Inhibitors
Gabriella Kervefors, Kumar Bhaskar Pal; Gergely L. Tolnai, Mukul Mahanti, Hakon Leffler, Ulf J. Nilsson* and Berit Olofsson*
Helv. Chim. Acta 2021, 104, e2000220. Link (open access) PDF

2020
Transition Metal-Free and Regioselective Vinylation of Phosphine Oxides and
H-Phosphinates with VBX reagents
Laura Castoldi, Adam A. Rajkiewicz and Berit Olofsson*
Chem. Commun. 2020, 56, 14389-14392. Link (open access) PDF

Electrophilic Vinylation of Thiols under Mild and Transition Metal-Free Conditions
Laura Castoldi, Ester Maria Di Tommaso, Marcus Reitti, Barbara Gräfen and Berit Olofsson*
Angew. Chem. Int. Ed. 2020, 59, 15642-15646. Link (open acces) PDF

2019

Edited book:

Patai's Chemistry of Functional Groups: The Chemistry of Hypervalent Halogen Compounds
Ed: Berit Olofsson, Ilan Marek, Zvi Rappoport, 2019. Link

The chapters are separately available online.

 

Cover picture

Serena Monticelli, Wolfgang Holzer, Thierry Langer, Alexander Roller, Berit Olofsson,* Vittorio Pace*
ChemSusChem 2019, 12, 1113. Link (open access) PDF

Sustainable Asymmetric Organolithium Chemistry: Enantio- and Chemoselective Acylations through Recycling of Solvent, Sparteine and Weinreb “Amine”
Serena Monticelli, Wolfgang Holzer, Thierry Langer, Alexander Roller, Berit Olofsson,* Vittorio Pace*
ChemSusChem 2019, 12, 1147-1154. Link (open access) PDF

2018

Inside front cover

Piret Villo, Gabriella Kervefors and Berit Olofsson*
Chem. Commun. 2018, 54, 8788. Link

Transition Metal-Free, Chemoselective Arylation of Thioamides Yielding Aryl Thioimidates or
N-Aryl Thioamides
Piret Villo, Gabriella Kervefors and Berit Olofsson*
Chem. Commun. 2018, 54, 8810-8813. Link (open access). PDF

Arylations promoted by hypervalent iodine reagents (Book chapter)
Piret Villo and Berit Olofsson*

In Patai's Chemistry of Functional Groups: The Chemistry of Hypervalent Halogen Compounds
Ed: Berit Olofsson, Ilan Marek, Zvi Rappoport, 2018
DOI: 10.1002/9780470682531.pat0950. Link

Regiospecific N-Arylation of Aliphatic Amines under Mild and Metal-Free Reaction Conditions
Nibadita Purkait, Gabriella Kervefors, Erika Linde and Berit Olofsson*
Angew. Chem. Int. Ed. 2018, 57, 11427-11431. Link (open access) PDF
Angew. Chem. 2018, 130, 11597-11601. Link (open access) PDF

Metal-Free Formal Synthesis of Phenoxazine
Gabriella Kervefors, Antonia Becker, Chandan Dey and Berit Olofsson*
Beilstein J. Org. Chem. 2018, 14, 1491–1497. Link (open access) PDF
Invited paper for a special issue on Hypervalent iodine chemistry.

Synthesis of Phenols and Aryl Silyl Ethers via Arylation of Complimentary Hydroxide Surrogates
Marcus Reitti, Ramani Gurubrahaman, Melanie Walther, Erik Lindstedt and Berit Olofsson*
Org. Lett. 2018, 20, 1785-1788. Link  Article on Request

2017
One-Pot Synthesis of Unsymmetric Diaryliodonium Salts from Iodine and Arenes
Erik Lindstedt, Marcus Reitti and Berit Olofsson*
J. Org. Chem. 2017, 82, 11909–11914 (invited for Special issue). Link  Article on Request


Competing Pathways in O-Arylations with Diaryliodonium Salts - Mechanistic Insights
Elin Stridfeldt, Erik Lindstedt, Marcus Reitti, Jan Blid, Per-Ola Norrby and Berit Olofsson*
"Hot Paper" in Chem. Eur. J. 2017, 23, 13249-13258. Link (open access) PDF
Among the top 10 most accessed papers in September!

2016

Arylation with Diaryliodonium Salts (Book chapter)
Berit Olofsson*

In Hypervalent Iodine Chemistry (Ed.: T. Wirth); Topics in Current Chemistry, Springer International Publishing, 2016, 373, 135-166. Link to the chapter; Link to the book.

Synthesis, Characterization and Unusual Reactivity of Vinylbenziodoxolones - Novel Hypervalent Iodine Reagents
Elin Stridfeldt, Alexandra Seemann, Marinus J. Bouma, Chandan Dey, Anne Ertan and Berit Olofsson*
"Hot Paper" in Chem. Eur. J. 2016, 22, 16066-16070. Link

Mild Synthesis of Sterically Congested Alkyl Aryl Ethers
Erik Lindstedt, Elin Stridfeldt and Berit Olofsson*
Org. Lett. 2016, 18, 4234-4237. Link (open access) PDF
Highlighted in Organic Synthesis Highlights (June 2017) and Organic Chemistry Portal.

Efficient O-Functionalization of Carbohydrates with Electrophilic Reagents
Gergely L. Tolnai, Ulf J. Nilsson and Berit Olofsson*
Angew. Chem. Int. Ed. 2016, 55, 11226-11230. Link (open access) PDF
Angew. Chem. 2016, 128, 11392-11396. Link (open access)

One-Pot C-H Functionalization of Arenes via Diaryliodonium Salts
Marcus Reitti, Piret Villo and Berit Olofsson*
Angew. Chem. Int. Ed. 2016, 55, 8928–8932. Link (open access) PDF
Angew. Chem. 2016, 128, 9074-9078. Link (open access)
Among the 10 most accessed papers in ACIE in June!
Highlighted in Organic Process Research & Development in August.

2015
Metal-Free C-Arylation of Nitro Compounds with Diaryliodonium Salts
Chandan Dey, Erik Lindstedt and Berit Olofsson*
Org. Lett. 2015, 17, 4554-4557. Link (Article on Request) 
Highlighted in Organic Chemistry Portal.

Synthesis of Chiral Diaryliodonium Salts
Michael Brown, Marion Delorme, Florence Malmedy, Joel Malmgren, Berit Olofsson,
Thomas Wirth*
Synlett 2015, 26, 1573-1577. Link (open access) PDF  

Metal-Free Arylation of Amides at Room Temperature
Fredrik Tinnis, Elin Stridfeldt, Helena Lundberg, Hans Adolfsson* and Berit Olofsson*
Org. Lett. 2015, 17, 2688-2691. Link (Article on Request)  
Highlighted in Organic Chemistry Portal.

2014

 

Increasing the Reactivity of Amide Bonds towards Organometallic Reagents: An Overview (Review)
Vittorio Pace,* Wolfgang Holzer and Berit Olofsson*

Adv. Synth. Catal. 2014, 356, 3697-3736. Link
Cover page: Adv. Synth. Catal. 2014, 356, 3686. Link


C-2 Selective Arylation of Indoles with Heterogeneous Nanopalladium and Diaryliodonium Salts
Joel Malmgren, Anuja Nagendiran, Cheuk-Wai Tai, Jan-E. Bäckvall,* and Berit Olofsson*
Chem. Eur. J. 2014, 20, 13531-13535.
Link
(open access)   PDF 

 

 

Metal-Free One-Pot Synthesis of Benzofurans
Raju Ghosh, Elin Stridfeldt and Berit Olofsson*
Chem. Eur. J. 2014, 20, 8888-8892. Link  

Room Temperature, Metal-Free Arylation of Aliphatic Alcohols
Raju Ghosh, Erik Lindstedt, Nazli Jalalian and Berit Olofsson*
ChemistryOpen, 2014, 3, 54-57. Link (open access) PDF 


Metal-Free Synthesis of N-Aryloxyimides and Aryloxyamines
Raju Ghosh and Berit Olofsson*
Org. Lett. 2014, 16, 1830-1832. Link (Article on request)  
Highligted in Organic Chemistry Portal.



α-Oxygenation of Carbonyl Compounds (Book chapter)

Marinus J. Bouma and Berit Olofsson*

In Comprehensive Organic Synthesis 2nd Ed., Vol. 7, Eds. G. A. Molander and P. Knochel, Oxford: Elsevier; 2014, 213-241. Link 

One-Pot Synthesis and Applications of N-Heteroaryl Iodonium Salts     
Marcin Bielawski, Joel Malmgren, Leticia M. Pardo, Ylva Wikmark and Berit Olofsson*
ChemistryOpen 2014, 3, 19-22. Link (open access) PDF  


2013

Purple fumes: the importance of iodine (Popular scientific review)
Frithjof C. Kuepper,* Martin C. Feiters, Berit Olofsson, Tatsuo Kaiho, Shozo Yanagida, Michael B. Zimmermann, Lucy J. Carpenter, George W. Luther III, Zunli Lu, Mats Jonsson and Lars Kloo

Science in School, 2013, Issue 27. PDF (open access)  

Metal-Free Synthesis of Aryl Ethers in Water
Erik Lindstedt, Raju Ghosh and Berit Olofsson*
Org. Lett. 2013, 15, 6070-6073. Link (Article on request)  
Highlighted in Organic Chemistry Portal.


Oxidative Rearrangement of Alkenes using In Situ Generated Iodine(III) Reagents
Anees Ahmad, Paulo Scarassati, Nazli Jalalian, Berit Olofsson and Luiz F. Silva, Jr.*
Tetrahedron Lett. 2013, 54, 5818-5820. Link  

Immunogenic and antioxidant effects of a pathogen-associated prenyl pyrophosphate in Anopheles gambiae
Bo Lindberg, Eleanor A. Merritt, Melanie Rayl, Chenxiao Liu, Ingela Parmryd, Berit Olofsson and Ingrid Faye*
PLoS One 2013, 8, e73868. Link (open access) PDF  

Arylation with Unsymmetrical Diaryliodonium Salts – a Chemoselectivity Study
Joel Malmgren, Stefano Santoro, Nazli Jalalian, Fahmi Himo* and Berit Olofsson*
Chem. Eur. J. 2013, 19, 10334-10342. Link (open access) PDF  


Synthesis of Koser's Reagent & Derivatives
Nazli Jalalian and Berit Olofsson*
Org. Synth. 2013, 90, 1-9. Link (open access) PDF  


2012
General One-Pot Synthesis of Alkynyliodonium Salts and Alkynyl Benziodoxolones from Aryl Iodides
Marinus J. Bouma and Berit Olofsson*
Chem. Eur. J. 2012, 18, 14242-14245. Link   


Metal-Free Arylation of Oxygen Nucleophiles with Diaryliodonium Salts
Nazli Jalalian, Tue B. Petersen and Berit Olofsson*
Chem. Eur. J. 2012, 18, 14140-14149. Link  

2011

Commemorating two centuries of iodine research: An interdisciplinary overview of current research (Review)

Frithjof C. Kuepper,* Martin C. Feiters, Berit Olofsson, Tatsuo Kaiho, Shozo Yanagida, Michael B. Zimmermann, Lucy J. Carpenter, George W. Luther III, Zunli Lu, Mats Jonsson and Lars Kloo*

Angew. Chem. Int. Ed. 2011, 50, 11598-11620. Link

Hypervalent Iodine Reagents in the Total Synthesis of Natural Products (Review)
Luiz F. Silva, Jr.* and Berit Olofsson
Nat. Prod. Rep. 2011, 28, 1722-1754. Link  

α-Functionalization of Carbonyl Compounds using Hypervalent Iodine Reagents (Review)
Eleanor A. Merritt and Berit Olofsson*
Synthesis 2011, 517-538. Link  

Metal-Free Synthesis of Indanes by Iodine(III)-Mediated Ring Contraction of 1,2-Dihydronaphthalenes
Fernanda A. Siqueira, Eloisa E. Ishikawa, André Fogaca, Andréa T. Faccio, Vânia M. T. Carneiro, Rafael R. S. Soares, Aline Utaka, Iris R. M. Tébéka, Marcin Bielawski, Berit Olofsson and Luiz F. Silva, Jr.*
J. Braz. Chem. Soc. 2011, 22, 1795-1807. Link    

Metal-Free Synthesis of Aryl Esters from Carboxylic Acids and Diaryliodonium Salts
Tue B. Petersen, Rehan Khan and Berit Olofsson*
Org. Lett. 2011, 13, 3462-3465. Link    
Highligted in Organic Chemistry Portal twice: 1st - 2nd link.


Synthesis of a Range of Iodine(III) Compounds Directly from Iodoarenes
Eleanor A. Merritt and Berit Olofsson*
Eur. J. Org. Chem. (Special Issue Women in Chemistry) 2011, 3690-3694. Link   


Room Temperature, Metal-Free Synthesis of Diaryl Ethers with Use of Diaryliodonium Salts
Nazli Jalalian, Eloisa E. Ishikawa, Luiz F. Silva Jr. and Berit Olofsson*
Org. Lett. 2011, 13, 1552-1555. Link   
Highligted in Organic Chemistry Portal.


2010
Facile Synthesis of Koser's Reagent & Derivatives from Iodine or Aryl Iodides
Eleanor A. Merritt, Vania M. T. Carneiro, Luiz F. Silva Jr. and Berit Olofsson*
J. Org. Chem. 2010, 75, 7416-7419. Link     
Highligted in Organic Chemistry Portal.


α-Arylation by Rearrangement: On the Reaction of Enolates with Diaryliodonium Salts
Per-Ola Norrby,* Tue B. Petersen, Marcin Bielawski and Berit Olofsson*
Chem. Eur. J. 2010, 16, 8251-8254. Link   


Design and Asymmetric Synthesis of Chiral Diaryliodonium Salts
Nazli Jalalian and Berit Olofsson*
Tetrahedron (Symposia-in-Print) 2010, 66, 5793-5800. Link    


2009

 

Diaryliodonium salts - a Journey from Obscurity to Fame (Review)
Eleanor A. Merritt and Berit Olofsson*

Angew. Chem. Int. Ed. 2009, 48, 9052-9070. Link  
Angew. Chem. 2009, 121, 9214-9234. Link  

Synthesis of Diaryliodonium Triflates using Environmentally Benign Oxidizing Agents
Eleanor A. Merritt, Joel Malmgren, Felix J. Klinke and Berit Olofsson*
Synlett 2009, 2277-2280. Link   

Efficient One-pot Synthesis of Bis(4-tert-Butylphenyl)Iodonium Triflate
Marcin Bielawski and Berit Olofsson*
Org. Synth. 2009, 86, 308-314. Link (open access) PDF   


2008
Regiospecific One-Pot Synthesis of Diaryliodonium Tetrafluoroborates from Arylboronic Acids and Aryl Iodides
Marcin Bielawski, David Aili and Berit Olofsson*
J. Org. Chem. 2008, 73, 4602-4607. Link    
Highligted in Organic Chemistry Portal.


One-Pot Synthesis of Diaryliodonium Salts using Toluenesulphonic Acid: A Fast Entry to Electron-Rich Diaryliodonium Tosylates and Triflates
Mingzhao Zhu, Nazli Jalalian and Berit Olofsson*
Synlett, 2008, 592-596. Link   SwePub
Highligted in Organic Chemistry Portal.


2007
Efficient and General One-Pot Synthesis of Diaryliodonium Triflates: Optimization, Scope and Limitations
Marcin Bielawski, Mingzhao Zhu and Berit Olofsson*
Adv. Synth. Catal. 2007, 349, 2610-2618. Link   


High-Yielding One-Pot Synthesis of Diaryliodonium Triflates from Arenes and Iodine or Aryl Iodides
Marcin Bielawski and Berit Olofsson*
Chem. Commun. 2007, 2521-2523. Link   


As Post Doc

 

Vinylepoxides in Organic Synthesis (book chapter)
Berit Olofsson and Peter Somfai*

In Aziridines and Epoxides in Organic Synthesis; Ed. A. Yudin; Wiley-VCH: Weinheim, 2006.
Link
  Review   

Divergent Asymmetric Synthesis of 3,5-Disubstituted Piperidines
Berit Olofsson, Krisztián Bogár, Ann-Britt L. Fransson and Jan-E. Bäckvall*
J. Org. Chem. 2006, 71, 8256-8260. Link    

Synthesis of Novel Heteroaryl Iodonium Salts and Enantioselective α-Arylation of Cyclohexanones
Berit Olofsson* and Varinder K. Aggarwal
Proc. 2nd Int. Conf. on Hypervalent Iodine, 2006, 47-50. PDF    

Efficient Synthesis of 2-Substituted Imidazoles by Palladium-Catalyzed Cross-Coupling with Benzylzinc Reagents
Josefin E. Utas, Berit Olofsson and Björn Åkermark*
Synlett 2006, 1965-1967. Link     


Enantioselective α-Arylation of Cyclohexanones with Diaryl Iodonium Salts: Application to the Synthesis of (–)-Epibatidine
Varinder K. Aggarwal* and Berit Olofsson
Angew. Chem. Int. Ed. 2005, 44, 5516-5519. Link   
Angew. Chem. 2005, 117, 5652-5655.


As PhD Student

Divergent Synthesis of D-erythro-Sphingosine, L-threo-Sphingosine and their Regioisomers
Berit Olofsson and Peter Somfai*
J. Org. Chem. 2003, 68, 2514-2517. Link  


Determination of the Relative Configuration of vic-Amino Alcohols
Berit Olofsson and Peter Somfai*
Tetrahedron Lett. 2003, 44, 1279-1281. Link  

 

Berit Olofsson
A Regio- and Stereodivergent Route to all Isomers of vic-Amino Alcohols

Doctoral Thesis, 2002. SwePub

A Regio- and Stereodivergent Route to all Isomers of vic-Amino Alcohols
Berit Olofsson and Peter Somfai*
J. Org. Chem. 2002, 67, 8574-8583. Link  

Synthesis of N-H Vinylaziridines: A Comparative Study
Berit Olofsson, Roel Wijtmans and Peter Somfai*
Tetrahedron 2002, 58, 5979-5982. Link  
Highligted in Organic Chemistry Portal.

A Regio- and Stereodivergent Route to all Isomers of vic-Amino Alcohols
Berit Olofsson and Peter Somfai*
Latvias J. Chem. 2002, 1, 69-78. PDF  

 

Berit Olofsson
A Regio- and Stereodivergent Synthesis of vic-Amino Alcohols

Licentiate Thesis, 2000. SwePub

A Regio- and Stereodivergent Synthesis of vic-Amino Alcohols
Berit Olofsson, Uttam Khamrai and Peter Somfai*
Org. Lett. 2000, 2, 4087-4089. Link  

Microwave-Assisted Aminolysis of Vinylepoxides
Ulf M. Lindström, Berit Olofsson and Peter Somfai*
Tetrahedron Lett. 1999, 40, 9273-9276. Link  

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