One of our targets is to deliver the efficient protocol for the regioselective synthesis of sulfenylated carbonyl compounds, with the understanding of mechanistic details. In this context, we reported on widely applicable protocols for user-friendly catalysts for synthesis of sulfenylated carbonyl compounds.

• S. Biswas, J. S. M. Samec, Chem. Commun. 2012, 48, 6586.
• S. Biswas, C.Dahlstrand, R. A. Watile, M. Kalek, F. Himo, J. S. M. Samec, Chem.Eur. J. 2013, 19, 17939.
• A. Watile, S. Biswas, J. S. M. Samec, Green Chem. 2013, 15, 3176.
• S. Biswas, R. A. Watile, J. S. M. Samec, Chem.Eur. J. 2014, 20, 2159.

The JS group has developed palladium catalyzed direct allylic substitution of non-derivatized allylic alcohol using electron deficient phosphite ligand to synthesize heterocyclic compounds. Our studies involved with investigation of the reaction mechanism and catalyst complex and also an application to natural product’s synthesis.

• S. Sawadjoon, J. S. M. Samec, Org. Biomol. Chem. 2011, 9, 2548.
• S. Sawadjoon, A. Orthaber, P. J. R. Sjöberg, L. Eriksson, J. S. M. Samec, Organometallic, 2014, 33, 249.
• S. Sawadjoon, P. Sjöberg, A. Orthaber, O. Matsson, J. S. M. Samec, Chem. Eur. J. 2014, 20, 1520.
• A. Bunrit, S. Sawadjoon, S. Tšupova, P. J. R. Sjöberg, J. S. M. Samec, J. Org. Chem. 2016, 81, 1450.

Our group is focusing on developing catalytic methodologies for the stereosspecific intramolecular substitution reaction of the non-derivertized alcohols as substrates in organic synthesis.  We also aim to increase the deep understanding of the catalytic activation of OH group of alcohols by various types of study such as kinetics study, spectroscopy and DFT calculation.

• A. Bunrit, C. Dahlstrand, S. K. Olsson, P. Srifa, G. Huang, A. Orthaber, P. J. R. Sjöberg, S. Biswas, F. Himo, J. S. M. Samec, J. Am. Chem. Soc. 2015, 137 , 4646.

The research interest of the group lie also in the field of lignin valorization. This project is focused at the intersection between the modeling and discovery new lignin like molecules reactions and reactivity, the elucidation of the reaction mechanism and active intermediates by means of DFT calculations and molecular dynamics, and, finally, application to valorize a real biomass feedstock.

• S. Sawadjoon, A. Lundstedt, J. S. M. Samec, ACS Catal. 2013, 3, 635.
• M. V. Galkin, S. Sawadjoon, V. Rohde, M. Dawange, J. S. M. Samec, ChemCatChem 2014, 6, 179.
• M. V. Galkin, J. S. M. Samec, ChemSusChem 2014, 7, 2154.
• M. Dawange, M. V. Galkin, J. S. M. Samec, ChemCatChem 2015, 7, 401.
• M. V. Galkin, C. Dahlstrand, J. S. M. Samec, ChemSusChem 2015, 8, 2187.
• M. V. Galkin, J. S. M. Samec, ChemSusChem 2016, 9, 1544.