| Preprints and postprints |
|---|
https://orcid.org/0000-0001-8303-4481/print
Recent Publications by the Group
Shi Y, Widmalm G, Korotkova N, Molenaar A, Holmes MA, McDougall S, Bijlsma JJE, van Sorge NM, Benedictus L. Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberis. Vet Res. 2025 Jul 7;56(1):139.
Wang W, Pang XJ, Wang M, Tian Y, Wu X, Pergolizzi G, Rejzek M, Field RA, Liu L, Widmalm G, Voglmeir J. Repurposing CDP-Tyvelose 2‑Epimerase Enables a GDP-Fucose-Based Fucosylation Pathway Starting from Sucrose. JACS Au. 2025 Jun 23;5(6):2689-2698.
Blasco P, Ståhle J, Thorsheim K, Furevi A, Siegbahn A, Tykesson E, Westergren-Thorsson G, Ellervik U, Widmalm G. Synthesis, conformational analysis and biological activity of xylopyranosyl sulfur-containing glycosides: dependence of sulfur atom configuration. RSC Adv. 2025 May 29;15(23):18010-18020.
Bateman KR, Scaletti Hutchinson E, Widmalm G, Miller MJ, Stenmark P. Structural and functional insights into Listeriamonocytogenes phage endolysin PlyP100: A promising food safety tool. J Biol Chem. 2025 May 27;301(7):110295.
Gao Y, Widmalm G, Im W. Dynamics and Interactions of OmpF Porin in an Asymmetric Bacterial Outer Membrane including LPS, ECA, and CPS. Biomacromolecules. 2025 Jun 9;26(6):3711-3720.
Fontana C, Weintraub A, Widmalm G. Structural elucidation of the O-antigen polysaccharide from shigatoxin-producing E. coli O179 using genetic information, NMR spectroscopy and the CASPER program. Carbohydr Res. 2025 Apr;550:109382.
Rush JS, Zamakhaeva S, Murner NR, Deng P, Morris AJ, Kenner CW, Black I, Heiss C, Azadi P, Korotkov KV, Widmalm G, Korotkova N. Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide. Nat Commun. 2025 Jan 22;16(1):954.
Ajay Castro S, Passmore IJ, Ndeh D, Shaw HA, Ruda A, Burns K, Thomson S, Nagar R, Alagesan K, Reglinski M, Lucas K, Abouelhadid S, Schwarz-Linek U, Mawas F, Widmalm G, Wren BW, Dorfmueller HC. Recombinant production platform for Group A Streptococcus glycoconjugate vaccines. NPJ Vaccines. 2025 Jan 22;10(1):16.
Hu ZX, Li SR, Xia QJ, Wang T, Voglmeir J, Widmalm G, Liu L. Enzymatic synthesis of N-formylated sialosides via a five-enzyme cascade. Org Biomol Chem. 2024 Sep 18;22(36):7485-7491.
Bånkestad M, Dorst KM, Widmalm G, Rönnols J. Carbohydrate NMR chemical shift prediction by GeqShift employing E(3) equivariant graph neural networks. RSC Adv. 2024 Aug 16;14(36):26585-26595.
Strobl S, Zucchetta D, Vašíček T, Monti A, Ruda A, Widmalm G, Heine H, Zamyatina A. Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4-specific LPS Mimetics with Picomolar Potency. Angew Chem Int Ed Engl. 2024 Sep 23;63(39):e202408421.
Rush JS, Zamakhaeva S, Murner NR, Deng P, Morris AJ, Kenner CW, Black I, Heiss C, Azadi P, Korotkov KV, Widmalm G, Korotkova N. Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide. bioRxiv. 2024 May 9;.
Widmalm G. Glycan Shape, Motions, and Interactions Explored by NMR Spectroscopy. JACS Au. 2024 Jan 22;4(1):20-39.
Dorst KM, Engström O, Angles d'Ortoli T, Mobarak H, Ebrahemi A, Fagerberg U, Whitfield DM, Widmalm G. On the influence of solvent on the stereoselectivity of glycosylation reactions. Carbohydr Res. 2024 Jan;535:109010.
Dorst KM, Widmalm G. Conformational Preferences at the Glycosidic Linkage of Saccharides in Solution as Deduced from NMR Experiments and MD Simulations: Comparison to Crystal Structures. Chemistry. 2024 Mar 12;30(15):e202304047.
Dorst KM, Widmalm G. NMR chemical shift prediction and structural elucidation of linker-containing oligo- and polysaccharides using the computer program CASPER. Carbohydr Res. 2023 Nov;533:108937.
Scaletti ER, Pettersson P, Patrick J, Shilling PJ, Westergren RG, Daley DO, Mäler L, Widmalm G, Stenmark P. Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis. J Biol Chem. 2023 Oct;299(10):105256.
Plazinski W, Angles d'Ortoli T, Widmalm G. Conformational flexibility of the disaccharide β-L-Fucp-(1→4)-α-D-Glcp-OMe as deduced from NMR spectroscopy experiments and computer simulations. Org Biomol Chem. 2023 Aug 30;21(34):6979-6994.
Wiseman B, Widmalm G, Högbom M. Alternating L4 loop architecture of the bacterial polysaccharide co-polymerase WzzE. Commun Biol. 2023 Aug 2;6(1):802.
Smith MJ, Gates EL, Widmalm G, Adams RW, Morris GA, Nilsson M. Resolving the complexity in human milk oligosaccharides using pure shift NMR methods and CASPER. Org Biomol Chem. 2023 May 17;21(19):3984-3990.
Kwon J, Ruda A, Azurmendi HF, Zarb J, Battistel MD, Liao L, Asnani A, Auzanneau FI, Widmalm G, Freedberg DI. Glycan Stability and Flexibility: Thermodynamic and Kinetic Characterization of Nonconventional Hydrogen Bonding in Lewis Antigens. J Am Chem Soc. 2023 May 10;145(18):10022-10034.
Gates EL, Smith MJ, Bradley JP, Johnson M, Widmalm G, Nilsson M, Morris GA, Adams RW, Castañar L. Ultra-selective, ultra-clean 1D rotating-frame Overhauser effect spectroscopy. Chem Commun (Camb). 2023 May 11;59(39):5854-5857.
Gao Y, Widmalm G, Im W. Modeling and Simulation of Bacterial Outer Membranes with Lipopolysaccharides and Capsular Polysaccharides. J Chem Inf Model. 2023 Mar 13;63(5):1592-1601.
Fontana C, Widmalm G. Primary Structure of Glycans by NMR Spectroscopy. Chem Rev. 2023 Feb 8;123(3):1040-1102.
Ruda A, Aytenfisu AH, Angles d'Ortoli T, MacKerell AD Jr, Widmalm G. Glycosidic α-linked mannopyranose disaccharides: an NMR spectroscopy and molecular dynamics simulation study employing additive and Drude polarizable force fields. Phys Chem Chem Phys. 2023 Jan 27;25(4):3042-3060.
Furevi A, Ståhle J, Muheim C, Gkotzis S, Daley DO, Udekwu KI, Widmalm G. Elucidation of the O-antigen structure of Escherichia coli O93 and characterization of its biosynthetic genes. Glycobiology. 2023 May 17;33(4):289-300.
Furevi A, Udekwu KI, Widmalm G. Structural elucidation of the O-antigen polysaccharide from Escherichia coli O125ac and biosynthetic aspects thereof. Glycobiology. 2022 Nov 22;32(12):1089-1100.
Riu F, Ruda A, Ibba R, Sestito S, Lupinu I, Piras S, Widmalm G, Carta A. Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview. Pharmaceuticals (Basel). 2022 Jul 29;15(8).
Auman D, Ecker F, Mader SL, Dorst KM, Bräuer A, Widmalm G, Groll M, Kaila VRI. Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ. J Am Chem Soc. 2022 Aug 31;144(34):15622-15632.
Furevi A, Ruda A, Angles d'Ortoli T, Mobarak H, Ståhle J, Hamark C, Fontana C, Engström O, Apostolica P, Widmalm G. Complete (1)H and (13)C NMR chemical shift assignments of mono-to tetrasaccharides as basis for NMR chemical shift predictions of oligo- and polysaccharides using the computer program CASPER. Carbohydr Res. 2022 Mar;513:108528.