The Szabó Research Group

Welcome to the Szabó Group

 

Please enjoy the visit of our web-site. Here You can find information about the research interest of the group, information on past and present members of the group, opening of Ph.D. and post-doctoral positions and current evets. Do not miss the Szabó groups's photo gallery.

 

Selected latest publications:

Full list of publications [click here]

J. Zhao, S. J. T. Jonker, D. N. Meyer, G. Schulz, C. D. Tran, L. Eriksson, K. J. Szabó*: Copper-Catalyzed Synthesis of Allenylboronic Acids. Access to Sterically Encumbered Homopropargylic Alcohols and Amines by Propargylboration Chem. Sci. 2018, 9, 3305 - 3312.

M. A. Cortes Gonzalez, P. Nordeman, A. Bermejo Gomez, D. N. Meyer, G. Antoni, M. Schou, K. J. Szabó*: [18F]Fluoro-benziodoxole: A no-carrier-added electrophilic fluorinating reagent. Rapid, simple radiosynthesis, purification and application for fluorine-18 labelling. Chem. Commun. 2018, 54, 4286-4289

B. K. Mai, K. J. Szabó,* F. Himo*: Mechanisms of Rh-Catalyzed Oxyfluorination and Oxytrifluoromethylation of Diazocarbonyl Compounds with Hypervalent Fluoroiodine. ACS Catal. 2018, 8, 4483-4492.

Wang, D.; de Wit, M. J. M.; Szabó, K. J.*: Synthesis of Densely Substituted Conjugated Dienes by Transition-metal-free Reductive Coupling of Allenylboronic Acids and Tosylhydrazones. J. Org. Chem. 2018, 83, 8786-8792..

B. K. Mai, K. J. Szabó,* F. Himo*: Mechanisms of Rh-Catalyzed Oxyaminofluorination and Oxyaminotrifluoromethylthiolation of Diazocarbonyl Compounds with Electrophilic Reagents. Org. Lett. 2018, 20, 6646-6649.

S. J. T. Jonker, C. Diner, G. Schulz, H. Iwamoto, L. Eriksson, K. J. Szabó*: Catalytic asymmetric propargyl- and allylboration of hydrazonoesters: a metal-free approach to sterically encumbered chiral α-amino acid derivatives. Chem. Commun., 2018, 54, 12852-12855.

M. Lübcke, D. Bezhan, K. J. Szabó*: Trifluoromethylthiolation-Arylation of Diazocarbonyl Compounds by Modified Hooz Multicomponent Coupling. Chem. Sci. 2019, 10, 5990-5995.

M. A. Cortés Gonzáles; X. Jiang, P. Nordeman, G. Antoni, K. Szabó*: Rhodium-mediated 18F-oxyfluorination of diazoketones using fluorine-18-containing hypervalent iodine reagent.  J. Chem. Commun. 2019, 55, 13358 - 13361.

X. Jiang, D. Meyer, D. Baran, M. A. Cortés González, K. J. Szabó*: Trifluoromethylthiolation, Trifluoromethylation and Arylation Reactions of Difluoro Enol Silyl Ethers J. Org. Chem. 2020, 85, 8311–8319. Highlighted in JOC 2020 Featured Articles: Unique, Inspiring, and Exceptionally Well-Done Chemistry

M. Lübcke, K. J. Szabó*: Diazocarbonyl Compounds in Organofluorine Chemistry; Synlett 2020, DOI: 10.1055/a-1297-6902.

O. Brea, K. J. Szabó*, F. Himo*: Mechanisms of Formation and Rearrangement of Benziodoxole-Based CF3 and SCF3 Transfer Reagents; J. Org. Chem., 2020, 85, 15577-15585.

Q.Wang§, M. Lübcke§, M. Biosca§, M. Hedberg, L. Eriksson, F. Himo*, K. J. Szabó*: Enantioselective Construction of Tertiary Fluoride Stereocenters by Organocatalytic Fluorocyclization; J. Am. Chem. Soc. 2020, 142, 20048-20057. §Contributed equally. Highlited in Synfacts: B. List, S. Brunen, S: Hypervalent Iodine Triggers Asymmetric Fluorocyclization toward Tertiary C–F Stereocenters; Synfacts 2021, 17, 0209.

S. J. T. Jonker§, R. Jayarajan§, T. Kireilis, M. Deliaval, L. Eriksson, K. J. Szabó*: Organocatalytic Synthesis of α-Trifluoromethyl Allylboronic Acids by Enantioselective 1,2-Borotropic Migration; J. Am. Chem. Soc. 2020, 142, 21254-21259. §Contributed equally. See Sybrand Jonker's presentation.

K. J. Szabó*: Fluorination, trifluoromethylation and trifluoromethylthiolation of alkenes, cyclopropanes and diazo compounds. In "Organofluorine Chemistry: Synthesis, Modeling, and Applications" K. J. Szabó, N. Selander, Eds. Wiley-VCH 2021, Chapter 6, 201-223.

Organofluorine Chemistry: Synthesis, Modeling, and Applications. K. J. Szabó, N. Selander, Eds. Wiley-VCH, 2021, ISBN: 978-3-527-82514-1

Full list of publications [click here]